Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529613 | 1.00 | MAPT (0.47) | MAPTALDH1A1GAAMAPK1GFER | |
| SCHEMBL10425412 | 0.91 | ALDH1A1 (0.48) | MAPTALDH1A1GAAMAPK1GFER | |
| SCHEMBL9017245 | 0.89 | ALDH1A1 (0.55) | MAPTALDH1A1GAAMAPK1GFER | |
| SCHEMBL9312760 | 0.85 | MAPT (0.44) | MAPTALDH1A1GAAMAPK1GFER | |
| SCHEMBL8152938 | 0.85 | CNR2 (0.48) | MAPTALDH1A1GAAMAPK1GFER | |
| SCHEMBL9312765 | 0.85 | MAPT (0.44) | MAPTALDH1A1GAAMAPK1GFER | |
| SCHEMBL8152939 | 0.85 | CNR2 (0.48) | MAPTALDH1A1GAAMAPK1GFER | |
| SCHEMBL8564034 | 0.84 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4EHPGDGSK3B | |
| SCHEMBL5070722 | 0.83 | MAOB (0.55) | MAPTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL14143137 | 0.83 | ALDH1A1 (0.47) | MAPTALDH1A1GAAMAPK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920645-B1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INC (US) | 2002-04-03 | — | — | EP | disclosed |
| US-6096246-A | POLYMER LENSES WITH RADIATION RESISTANT NAPHTHOPYRAN MIXTURES | CORNING INCORPORATED (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0920645-A4 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INC (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0920645-A1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INCORPORATED (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998004937-A1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INCORPORATED (US) | 1998-02-05 | — | — | WO | disclosed |