Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616914 | 0.93 | ALDH1A1 (0.48) | GABRR1CYP1A2ALDH1A1MEN1NPC1 | |
| SCHEMBL7843927 | 0.86 | ALDH1A1 (0.42) | BLMALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL28216537 | 0.86 | CHRM1 (0.40) | GABRR1CYP1A2ACE2ALDH1A1MEN1 | |
| SCHEMBL9507272 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MEN1NPC1KMT2ALMNA | |
| SCHEMBL29054984 | 0.84 | ALDH1A1 (0.40) | GABRR1CYP1A2ACE2ALDH1A1LMNA | |
| SCHEMBL11072837 | 0.84 | CYP3A4 (0.50) | GABRR1CYP1A2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL11072835 | 0.84 | CYP3A4 (0.50) | GABRR1CYP1A2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL13483255 | 0.83 | SMN1; SMN2 (0.45) | ALDH1A1MEN1NPC1KMT2ALMNA | |
| SCHEMBL28182020 | 0.83 | ALDH1A1 (0.43) | BLMALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL113543 | 0.83 | SMN1; SMN2 (0.45) | ALDH1A1MEN1NPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014257-A2 | SYNTHESIS OF Α,Ω-DIESTERS | CONSORZIO INTERUNIVERSITARIO NAZIONALE LA CHIMICA PER L'AMBIENTE (IT) | 2002-02-21 | — | — | WO | disclosed |
| EP-0765857-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | MITSUBISHI RAYON CO (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5773240-A | Optically active α-substituted carboxylic acid derivatives and method for producing the same | MITSUBISHI RAYON CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0765857-A1 | OPTICALLY ACTIVE ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | MITSUBISHI RAYON CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |