SCHEMBL7530302

SCHEMBL7530302

CC(=O)C(Cl)Cc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.32
ITGB1 P05556 2/20 0.31
ITGA4 P13612 2/20 0.31
ITGB7 P26010 2/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7894565 0.84 ITGB1 (0.31) ITGB1ITGA4ITGB7MEN1KMT2A
SCHEMBL9423157 0.83 RORC (0.35) NOTUMMEN1KMT2A
SCHEMBL7162858 0.83
SCHEMBL9423300 0.82 MEN1 (0.31) MEN1KMT2A
SCHEMBL9423041 0.79 TDP1 (0.40) NOTUMMEN1KMT2A
SCHEMBL31442410 0.77 COMT (0.37) NOTUMKMT2A
Ethylene SCHEMBL9423310 0.77 TDP1 (0.39) NOTUMMEN1KMT2A
SCHEMBL1807362 0.77 TDP1 (0.52) NOTUMMEN1KMT2A
SCHEMBL29576263 0.77 TDP1 (0.40) NOTUMMEN1KMT2A
SCHEMBL9168174 0.77 TDP1 (0.40) NOTUMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770067-B1 SUBSTITUTED CINNAMIC OXIME AND HYDROXAMIDE DERIVATIVES BASF AG (DE) 2002-03-13 EP disclosed
US-6013606-A HERBICIDES BASF AKTEINGESELLSCHAFT (DE) 2000-01-11 US disclosed