Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 3/20 | 0.44 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | NPY2R | P49146 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416564 | 1.00 | MMP2 (0.48) | MMP2L3MBTL1MASP2F2EPHX2 | |
| SCHEMBL7530381 | 1.00 | MMP2 (0.48) | MMP2L3MBTL1MASP2F2EPHX2 | |
| SCHEMBL27118430 | 0.96 | MMP2 (0.50) | MMP2L3MBTL1MASP2F2EPHX2 | |
| SCHEMBL27116140 | 0.92 | NPY1R (0.47) | MMP2MASP2F2EPHX2SPHK1 | |
| SCHEMBL30905443 | 0.88 | NPY4R (0.55) | SPHK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7530347 | 0.88 | CYP2D6 (0.49) | MMP2MMP8 | |
| Water SCHEMBL8529560 | 0.87 | SPHK1 (0.48) | SPHK1NPY4RNPY1RNPY2RNPY5R | |
| Hydrochloric Acid SCHEMBL6380920 | 0.87 | HDAC8 (0.48) | MMP2MMP8 | |
| SCHEMBL27113228 | 0.85 | MME (0.51) | L3MBTL1MASP2F2EPHX2 | |
| SCHEMBL6864434 | 0.83 | HPGD (0.46) | MMP2NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | disclosed |
| EP-0564588-A4 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS | — | 1993-12-29 | — | — | EP | disclosed |
| EP-0564588-A1 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS. | ABBOTT LAB (US) | 1993-10-13 | — | — | EP | disclosed |