SCHEMBL753052

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16875924	0.84	HSD17B10 (0.66)	HSD17B10MAPK1KMT2ATSHRLMNA
	SCHEMBL671242	0.81	TSHR (0.63)	HSD17B10MAPK1KMT2ATSHRLMNA
	SCHEMBL24628398	0.81	KMT2A (0.59)	HSD17B10MAPK1KMT2ATSHRLMNA
	SCHEMBL21054803	0.81	HSD17B10 (0.55)	HSD17B10MAPK1KMT2ATSHRLMNA
	SCHEMBL16095293	0.79	LMNA (0.63)	HSD17B10MAPK1KMT2ATSHRLMNA
	SCHEMBL3611556	0.79	MAPT (0.97)	HSD17B10MAPK1KMT2ATSHRLMNA
	SCHEMBL3084412	0.79	LMNA (0.63)	HSD17B10MAPK1KMT2ATSHRLMNA
	SCHEMBL2902778	0.79	HSD17B10 (0.59)	HSD17B10MAPK1KMT2ATSHRLMNA
	SCHEMBL25561729	0.78	KMT2A (0.59)	HSD17B10MAPK1KMT2ATSHRLMNA
	SCHEMBL18097766	0.78	TSHR (0.55)	HSD17B10MAPK1KMT2ATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.