Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.59 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24071234 | 1.00 | HSD17B10 (0.59) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL26728602 | 1.00 | HSD17B10 (0.59) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL26728759 | 1.00 | HSD17B10 (0.59) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL4475727 | 1.00 | HSD17B10 (0.59) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL4475724 | 1.00 | HSD17B10 (0.59) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL26728614 | 0.98 | HSD17B10 (0.61) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL16312506 | 0.98 | HSD17B10 (0.61) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL29263924 | 0.87 | HSD17B10 (0.67) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL30508486 | 0.82 | — | — | |
| SCHEMBL30388595 | 0.82 | ACHE (0.50) | HSD17B10KMT2ATARDBPCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1131226-C | Novel 1,2-amylic cycle disulfide, its preparation process and medicinal compoisitions containing same | ADIR (FR) | 2003-12-17 | — | — | CN | disclosed |
| EP-1010698-B1 | 1,2-dithiolane derivatives, their process of preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-27 | — | — | EP | disclosed |
| US-6150358-A | USEFUL IN THE TREATMENT OF DISEASE FOR WHICH THE USE OF ANTI-OXIDATION AGENT IS REQUIERED SUCH AS NEURODEGENRATIVE DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-21 | — | — | US | disclosed |
| EP-1010698-A1 | 1,2-dithiolane derivatives, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |
| CN-1257072-A | Novel 1,2-amylic cycle disulfide, its preparation process and medicinal compoisitions containing same | ADIR (FR) | 2000-06-21 | — | — | CN | disclosed |