Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779960 | 0.82 | — | — | |
| SCHEMBL779959 | 0.82 | — | — | |
| Acetone SCHEMBL28356790 | 0.73 | — | — | |
| Acetic Acid SCHEMBL10410245 | 0.71 | — | — | |
| Bicarbonate SCHEMBL6422023 | 0.70 | — | — | |
| Methyl Alcohol SCHEMBL6662223 | 0.69 | — | — | |
| Bicarbonate SCHEMBL7711200 | 0.68 | — | — | |
| Bicarbonate SCHEMBL27558295 | 0.68 | — | — | |
| SCHEMBL29225954 | 0.68 | — | — | |
| SCHEMBL887973 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128213-A1 | Sixteen-membered macrolide compounds | KOSAN BIOSCIENCES, INC. | 2002-09-12 | — | — | US | disclosed |
| US-20020111317-A1 | Sixteen-membered macrolide compounds | KOSAN BIOSCIENCES, INC. | 2002-08-15 | — | — | US | disclosed |
| WO-2002032916-A2 | SIXTEEN-MEMBERED MACROLIDE COMPOUNDS | KOSAN BIOSCIENCES, INC. (US) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111317-A1 | Sixteen-membered macrolide compounds | NOP2, NSUN3, MRPS23 | TSHR 882/4885 |
| US-20020128213-A1 | Sixteen-membered macrolide compounds | NOP2, NSUN3, MRPS23 | TSHR 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.