NOP2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to NOP2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effect of Antibiotics on Enteric Neurons and Glia	PHASE4	COMPLETED
Effect of WHO-yaws Elimination Strategy in Lihir Island, Papua New Guinea	PHASE3	COMPLETED
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders.	PHASE1/PHASE2	RECRUITING
Application of mRNA Immunotherapy Technology in Epstein-Barr Virus-related Refractory Malignant Tumors	PHASE1	ACTIVE_NOT_RECRUITING
Trichomonas Vaginalis Genotyping in Upper Egypt	nan	UNKNOWN
The Gut Microbiome in Diverticulitis and Diverticulosis	nan	WITHDRAWN
Abundance of Lactobacillus in Endometrium Affected by Chronic Endometritis	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Novel Diagnostic Methods to Identify External Ventricular Drain Associated Infections	nan	UNKNOWN
NUTRIPROTECT-Children Nutrition as a Protective or Health-risk Factor	nan	COMPLETED
Microbiome and Metagenome in Percutaneous Osseointegrated Prostheses (MMPOP)	nan	COMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Study of Specimens From Young Patients With Neuroblastoma	nan	COMPLETED
miR-155 Expression in Episodic and Chronic Migraine	nan	UNKNOWN
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC	nan	UNKNOWN
Clinical Impact of 16S rDNA PCR	nan	UNKNOWN
Role of Sarcopenia and Nutritional/Physical Therapy Intervention in Post-TIPS Hepatic Encephalopathy	nan	UNKNOWN
Effect of Dietary Supplements on the Oral Microbiome	nan	ACTIVE_NOT_RECRUITING
Study of Faecal Bacteria Detection in Early Screening and Diagnosis of GC	nan	UNKNOWN
Elucidating the Microbiome in Patients With Recurrent Pregnancy Loss	nan	UNKNOWN
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
Effect of Beta-Glucan on Cholesterol Lowering	nan	COMPLETED
The Human Microbiome and IVF Outcomes	nan	COMPLETED
Treatment of Initial Clostridium Difficile Infection	nan	COMPLETED
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas	nan	ACTIVE_NOT_RECRUITING
Microbiome Establishment in Preterm Infants	nan	UNKNOWN
Identification of Novel Bio-markers for Environmental Enteropathy in Children Using an Evidence Based Approach	nan	COMPLETED
Multi-omics Dissection of Gut Microbiome Engraftment During FMT	nan	NOT_YET_RECRUITING
Impact of Bariatric and Metabolic Surgery on the Reduction of Premature Aging.	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NOP2 binder may also engage these)

Protein	Name	Similarity
Q922K7	—	1.000	Q922K7 →
Q8WML3	—	0.994	Q8WML3 →
Q8VYM6	—	0.993	Q8VYM6 →
Q8BZ21	—	0.992	Q8BZ21 →
Q9BQK8	—	0.992	Q9BQK8 →
Q24595	—	0.992	Q24595 →
A6QP06	—	0.991	A6QP06 →
Q9GZR2	—	0.991	Q9GZR2 →
Q8RWK8	—	0.991	Q8RWK8 →
Q99PI5	—	0.990	Q99PI5 →
Q8BMD7	—	0.990	Q8BMD7 →
Q8BWQ5	—	0.990	Q8BWQ5 →
Q6PAQ4	—	0.990	Q6PAQ4 →
BPTF	Nucleosome-remodeling factor subunit BPTF	0.990	landscape →
KAT6B	Histone acetyltransferase KAT6B	0.989	landscape →
Q8CCG4	—	0.989	Q8CCG4 →
Q76LL6	—	0.989	Q76LL6 →
A0JMK9	—	0.989	A0JMK9 →
KDM4B	Lysine-specific demethylase 4B	0.989	landscape →
DHX29	ATP-dependent RNA helicase DHX29	0.989	landscape →
LIPE	Hormone-sensitive lipase	0.989	landscape →
Q5VZ18	—	0.989	Q5VZ18 →
Q2PFD7	—	0.989	Q2PFD7 →
Q99PI4	—	0.989	Q99PI4 →
BMP2K	BMP-2-inducible protein kinase	0.989	landscape →
P61406	—	0.989	P61406 →
B4R4H1	—	0.989	B4R4H1 →
A0A0R4IZ84	—	0.989	A0A0R4IZ84 →
Q9FG73	—	0.989	Q9FG73 →
Q8VID5	—	0.989	Q8VID5 →