Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316625 | 0.80 | KDM4E (0.45) | MAOBMAOAADORA2AKDM4EALDH1A1 | |
| SCHEMBL7524591 | 0.75 | ALDH1A1 (0.56) | MAOBMAOAADORA2AKDM4EALDH1A1 | |
| SCHEMBL5437603 | 0.66 | ALDH1A1 (0.50) | ADORA2AKDM4EALDH1A1MEN1USP2 | |
| SCHEMBL5448218 | 0.66 | ALDH1A1 (0.53) | ADORA2AKDM4EALDH1A1MEN1USP2 | |
| SCHEMBL6316654 | 0.65 | ALDH1A1 (0.65) | MAOBMAOAADORA2AKDM4EALDH1A1 | |
| SCHEMBL5439939 | 0.64 | KDM4E (0.57) | MAOBMAOAADORA2AKDM4EALDH1A1 | |
| SCHEMBL5454832 | 0.64 | ALDH1A1 (0.50) | ADORA2AKDM4EALDH1A1MEN1USP2 | |
| SCHEMBL5440379 | 0.64 | ALDH1A1 (0.54) | MAOBMAOAADORA2AKDM4EALDH1A1 | |
| SCHEMBL5438439 | 0.64 | ALDH1A1 (0.50) | ADORA2AKDM4EALDH1A1MEN1USP2 | |
| SCHEMBL8865210 | 0.63 | C1S (0.56) | ALDH1A1MEN1GAAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187615-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. Leuven Research & Development (BE) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000045800-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-08-10 | — | — | WO | disclosed |