Ethylene Glycol

Ethylene Glycol

SCHEMBL7530947

O=C(O)c1ccc(C(=O)Oc2ccc3cc(C(=O)O)ccc3c2)cc1.OCCO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.58
MAPT P10636 2/20 0.58
MEN1 O00255 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
KDM4E B2RXH2 1/20 0.56
HGFAC Q04756 2/20 0.48
TMPRSS2 O15393 1/20 0.48
MLNR O43193 1/20 0.48
ALDH1A1 P00352 1/20 0.48
F2 P00734 1/20 0.48
C1R P00736 1/20 0.48
F10 P00742 1/20 0.48
PLG P00747 1/20 0.48
F12 P00748 1/20 0.48
LMNA P02545 1/20 0.48
ITGB3 P05106 1/20 0.48
HPN P05981 1/20 0.48
KLK1 P06870 1/20 0.48
PRSS1 P07477 1/20 0.48
CHRM2 P08172 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL4127752 0.95 KMT2A (0.57) KMT2AMAPTMEN1TDP1KDM4E
SCHEMBL5698841 0.93 KMT2A (0.66) KMT2AMAPTMEN1TDP1KDM4E
SCHEMBL6052888 0.92 KMT2A (0.68) KMT2AMAPTMEN1TDP1KDM4E
SCHEMBL5698842 0.88 KDM4E (0.65) KMT2AMAPTMEN1TDP1KDM4E
SCHEMBL10778099 0.87 KMT2A (0.77) KMT2AMAPTMEN1TDP1KDM4E
Ethylene Glycol SCHEMBL4141445 0.86 PARP10 (0.55) KMT2AMAPTMEN1TDP1TMPRSS2
SCHEMBL9793342 0.85 KMT2A (0.60) KMT2AMAPTMEN1TDP1KDM4E
Terephthalic Acid SCHEMBL7993200 0.84 KDM4E (0.57) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL6052916 0.84 KMT2A (0.58) KMT2AMAPTMEN1TDP1KDM4E
Terephthalic Acid SCHEMBL15663256 0.83 KMT2A (0.49) KMT2AMAPTMEN1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1195408-A1 LIQUID-CRYSTAL POLYESTER RESIN COMPOSITION KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUSHO (JP) 2002-04-10 EP disclosed