Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 12/20 | 0.53 |
| ▸ | GPR17 | Q13304 | 3/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191778 | 0.85 | FBP1 (0.66) | FBP1GPR17 | |
| SCHEMBL7383934 | 0.80 | FBP1 (0.73) | FBP1 | |
| SCHEMBL29062863 | 0.79 | GPR17 (0.71) | FBP1GPR17 | |
| SCHEMBL7452457 | 0.79 | GPR17 (0.49) | FBP1GPR17 | |
| SCHEMBL7382647 | 0.79 | GPR17 (0.52) | FBP1GPR17 | |
| SCHEMBL25288592 | 0.79 | GPR17 (0.49) | GPR17 | |
| SCHEMBL2884256 | 0.76 | APEX1 (0.43) | FBP1GPR17SERPINE1 | |
| SCHEMBL4051970 | 0.74 | FBP1 (0.54) | FBP1 | |
| SCHEMBL2232715 | 0.72 | KDM4E (0.68) | GPR17 | |
| SCHEMBL28713546 | 0.72 | KDM4E (0.68) | GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196436-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002424-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | DU PONT PHARMACEUTICALS COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |