Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963008 | 0.87 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL30963009 | 0.87 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL29930396 | 0.87 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL3858691 | 0.87 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL19216393 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL31500431 | 0.83 | F2R (0.33) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL5630244 | 0.82 | CNR2 (0.41) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL29145739 | 0.82 | CNR2 (0.41) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL2491248 | 0.82 | CNR2 (0.41) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9871733 | 0.82 | CNR2 (0.41) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | claimed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | claimed |