Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.64 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950491 | 0.80 | PRKAA2 (0.68) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| Methane SCHEMBL27947407 | 0.80 | PRKAA2 (0.72) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL28803542 | 0.80 | PRKAA2 (0.68) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL526202 | 0.80 | PRKAA2 (0.68) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL14114892 | 0.80 | PRKAA2 (0.68) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL27512912 | 0.80 | PRKAA2 (0.68) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL5183647 | 0.80 | RXRA (0.64) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL5183501 | 0.80 | RXRA (0.64) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| Bromide SCHEMBL3711240 | 0.79 | PRKAA2 (0.67) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL6072090 | 0.79 | ADORA2A (0.56) | ADORA1ADORA2AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361215-B1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-03-21 | — | — | EP | claimed |
| CN-1237053-C | Process for producing quinoline carboxaldehyde derivative and intermediate thereof | NISSAN CHEMICAL IND LTD (JP) | 2006-01-18 | — | — | CN | claimed |
| US-6841681-B2 | Process for producing quinoline carboxyaldehyde derivative and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-01-11 | — | — | US | claimed |
| US-20040077866-A1 | Process for producing quinoline carboxyaldehyde derivative and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-22 | — | — | US | claimed |
| CN-1491215-A | Process for producing quinoline carboxaldehyde derivative and intermediate thereof | �ղ���ѧ��ҵ��ʽ���� | 2004-04-21 | — | — | CN | claimed |
| EP-1361215-A1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2003-11-12 | — | — | EP | claimed |
| EP-1361215-B1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-1361215-B1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-1361215-B1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-03-21 | — | — | EP | disclosed |
| CN-1237053-C | Process for producing quinoline carboxaldehyde derivative and intermediate thereof | NISSAN CHEMICAL IND LTD (JP) | 2006-01-18 | — | — | CN | disclosed |
| CN-1237053-C | Process for producing quinoline carboxaldehyde derivative and intermediate thereof | NISSAN CHEMICAL IND LTD (JP) | 2006-01-18 | — | — | CN | disclosed |
| US-6841681-B2 | Process for producing quinoline carboxyaldehyde derivative and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-01-11 | — | — | US | disclosed |
| US-6841681-B2 | Process for producing quinoline carboxyaldehyde derivative and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-01-11 | — | — | US | disclosed |
| US-20040077866-A1 | Process for producing quinoline carboxyaldehyde derivative and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
| CN-1491215-A | Process for producing quinoline carboxaldehyde derivative and intermediate thereof | �ղ���ѧ��ҵ��ʽ���� | 2004-04-21 | — | — | CN | disclosed |
| CN-1491215-A | Process for producing quinoline carboxaldehyde derivative and intermediate thereof | �ղ���ѧ��ҵ��ʽ���� | 2004-04-21 | — | — | CN | disclosed |
| EP-1361215-A4 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| EP-1361215-A1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2003-11-12 | — | — | EP | disclosed |
| EP-1361215-A1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002064569-A1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | UBE INDUSTRIES, LTD. (JP) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077866-A1 | Process for producing quinoline carboxyaldehyde derivative and intermediate thereof | CPNE4, CYP3A4, CYP4B1 | PRKAA2 2622/4885RXRA 4470/4885NR1I2 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.