Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 3/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.52 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | JAK3 | P52333 | 2/20 | 0.52 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.52 |
| ▸ | MELK | Q14680 | 2/20 | 0.52 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.52 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.52 |
| ▸ | CSNK1G3 | Q9Y6M4 | 2/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | FECH | P22830 | 1/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599945 | 0.84 | MAP3K5 (0.50) | CLK2DYRK1ADYRK3JAK2PRKD3 | |
| SCHEMBL5378711 | 0.81 | MAPK8 (0.54) | CLK2DYRK1ADYRK3JAK2PRKD3 | |
| SCHEMBL5375066 | 0.81 | MAP3K5 (0.47) | CLK2DYRK1ADYRK3JAK2PRKD3 | |
| SCHEMBL8252245 | 0.80 | MAP3K5 (0.56) | CLK2DYRK1ADYRK3JAK2PRKD3 | |
| SCHEMBL8365703 | 0.78 | MKNK1 (0.60) | CLK2DYRK1ADYRK3JAK2PRKD3 | |
| SCHEMBL5382298 | 0.77 | GAK (0.56) | CLK2DYRK1ADYRK3JAK2PRKD3 | |
| SCHEMBL5372315 | 0.77 | IDO1 (0.69) | CLK2DYRK1ADYRK3JAK2PRKD3 | |
| SCHEMBL8257010 | 0.77 | ENPP2 (0.69) | CLK2DYRK1ADYRK3JAK2PRKD3 | |
| SCHEMBL5381716 | 0.76 | MAP3K5 (0.54) | CLK2DYRK1ADYRK3JAK2PRKD3 | |
| SCHEMBL5375071 | 0.75 | MAP3K5 (0.51) | CLK2DYRK1ADYRK3JAK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103229-A1 | Indazole derivatives as JNK inhibitors and compositions and methods related thereto | SIGNAL PHARMACEUTICALS, LLC | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103229-A1 | Indazole derivatives as JNK inhibitors and compositions and methods related thereto | MAP3K7, MAP3K1, MAP3K8 | CLK2 322/4885DYRK1A 784/4885DYRK3 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.