Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049877 | 0.94 | MAPT (0.61) | MAPTKDM4EFAAHLMNASMN1; SMN2 | |
| SCHEMBL7532406 | 0.87 | MAPT (0.65) | MAPTKDM4EFAAHLMNAALDH1A1 | |
| SCHEMBL7049538 | 0.83 | MAPT (0.54) | MAPTKDM4EFAAHLMNAMEN1 | |
| SCHEMBL7054493 | 0.81 | MAPT (0.68) | MAPTKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL7609878 | 0.77 | MAPT (0.60) | MAPTKDM4EHTTMEN1KMT2A | |
| SCHEMBL8576007 | 0.77 | MAPT (0.65) | MAPTKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL7609940 | 0.76 | MAPT (0.58) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL7528425 | 0.75 | MAPT (1.00) | MAPTKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL8065139 | 0.74 | MAPT (0.72) | MAPTKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL3841693 | 0.73 | MAPT (0.75) | MAPTKDM4EALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488474-B1 | Herbicidal carboxamide derivatives | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-5384305-A | Plant growth regulators | SHELL RESEARCH LIMITED (GB) | 1995-01-24 | — | — | US | disclosed |
| EP-0488474-A1 | Herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-06-03 | — | — | EP | disclosed |