SCHEMBL7532406

SCHEMBL7532406

CCCCNC(=O)c1cccc(Oc2cccc(C(F)(F)F)c2)n1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.65
LMNA P02545 1/20 0.49
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48
SCN9A Q15858 10/20 0.48
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
KDM4E B2RXH2 1/20 0.46
FAAH O00519 1/20 0.46
SCN10A Q9Y5Y9 2/20 0.46
GPR52 Q9Y2T5 1/20 0.45
MRGPRX4 Q96LA9 1/20 0.44
TP53BP1 Q12888 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7054493 0.94 MAPT (0.68) MAPTALDH1A1POLBSCN9AKDM4E
SCHEMBL7532057 0.87 MAPT (0.59) MAPTLMNAALDH1A1POLBHDAC3
SCHEMBL8065139 0.83 MAPT (0.72) MAPTALDH1A1POLBKDM4ERAB9A
SCHEMBL3841693 0.83 MAPT (0.75) MAPTALDH1A1POLBKDM4ERAB9A
SCHEMBL7055040 0.81 MAPT (0.57) MAPTALDH1A1POLBSCN9AKDM4E
SCHEMBL7052329 0.81 MAPT (0.72) MAPTALDH1A1POLBSCN9AKDM4E
SCHEMBL7049877 0.81 MAPT (0.61) MAPTLMNAALDH1A1POLBSCN9A
SCHEMBL8573524 0.80 MAPT (0.71) MAPTALDH1A1POLBKDM4ERAB9A
SCHEMBL7528425 0.79 MAPT (1.00) MAPTALDH1A1POLBSCN9AKDM4E
SCHEMBL7953536 0.79 MAPT (0.69) MAPTALDH1A1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0488474-B1 Herbicidal carboxamide derivatives BASF AG (DE) 2002-04-17 EP disclosed
US-5384305-A Plant growth regulators SHELL RESEARCH LIMITED (GB) 1995-01-24 US disclosed
EP-0488474-A1 Herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-06-03 EP disclosed