Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844442 | 1.00 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL521825 | 1.00 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL27965774 | 1.00 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL10893415 | 1.00 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL35081 | 1.00 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL28682532 | 0.97 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Methyl Ester SCHEMBL6744119 | 0.97 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL7921491 | 0.97 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Butadiene SCHEMBL3320515 | 0.97 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL263473 | 0.97 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092555-B1 | A method for making a lithographic printing plate involving on-press development | AGFA GEVAERT (BE) | 2002-08-21 | — | — | EP | disclosed |
| EP-0770497-B1 | A method for making a lithographic printing plate involving development by plain water | AGFA GEVAERT (BE) | 2002-04-03 | — | — | EP | disclosed |
| EP-1092555-A1 | A method for making a lithographic printing plate involving on-press development | AGFA-GEVAERT N.V. (BE) | 2001-04-18 | — | — | EP | disclosed |
| US-6001536-A | USING A HYDROPHOBIC THERMOPLASTIC POLYMER PARTICLES IN HYDROPHILIC BINDER | AGFA-GEVAERT, N.V. (BE) | 1999-12-14 | — | — | US | disclosed |
| EP-0770497-A1 | A method for making a lithographic printing plate involving development by plain water | AGFA-GEVAERT N.V. (BE) | 1997-05-02 | — | — | EP | disclosed |