Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | GLA | P06280 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 3/20 | 0.42 |
| ▸ | SLC9A5 | Q14940 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4693743 | 0.99 | SCNN1A (0.41) | SCNN1AALDH1A1GLAHSD17B10KDM4E | |
| SCHEMBL7527745 | 0.99 | SCNN1A (0.41) | SCNN1AALDH1A1GLAHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL4751466 | 0.97 | ALDH1A1 (0.43) | SCNN1AALDH1A1GLAHSD17B10KDM4E | |
| SCHEMBL4413401 | 0.94 | SCNN1A (0.38) | SCNN1AALDH1A1GLAHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL6013438 | 0.89 | ALDH1A1 (0.36) | SCNN1AALDH1A1GLAHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL4417773 | 0.87 | KDM4E (0.39) | SCNN1AALDH1A1GLAHSD17B10KDM4E | |
| Bromide SCHEMBL4693421 | 0.86 | SCNN1A (0.44) | SCNN1AALDH1A1GLAHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL4693835 | 0.85 | KDM4E (0.46) | SCNN1AALDH1A1GLAHSD17B10KDM4E | |
| Bromide SCHEMBL4789642 | 0.85 | SCNN1A (0.43) | SCNN1AALDH1A1GLAHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL6013436 | 0.84 | KDM4E (0.38) | SCNN1AALDH1A1GLAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020158255-A1 | Conjugates of sodium channel blockers and methods of using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-10-31 | — | — | US | disclosed |