Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.70 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GOT1 | P17174 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558228 | 0.84 | EPHX2 (0.91) | EPHX2ACHECYP2C9CYP2C19POLB | |
| SCHEMBL5535039 | 0.83 | ACHE (0.66) | EPHX2ACHECYP2C9CYP2C19POLB | |
| SCHEMBL5535035 | 0.83 | ACHE (0.66) | EPHX2ACHECYP2C9CYP2C19POLB | |
| SCHEMBL12655774 | 0.83 | ACHE (0.75) | EPHX2ACHEMAPT | |
| SCHEMBL13873283 | 0.82 | EPHX2 (1.00) | EPHX2ACHECYP2C9CYP2C19POLB | |
| SCHEMBL20236394 | 0.80 | EPHX2 (0.75) | EPHX2ACHECYP2C9CYP2C19POLB | |
| SCHEMBL4393722 | 0.80 | EPHX2 (0.75) | EPHX2ACHECYP2C9CYP2C19POLB | |
| SCHEMBL13634099 | 0.80 | EPHX2 (0.75) | EPHX2CYP2C9CYP2C19POLBKMT2A | |
| SCHEMBL23419094 | 0.79 | EPHX2 (0.73) | EPHX2CYP2C9CYP2C19POLB | |
| SCHEMBL22218765 | 0.79 | EPHX2 (0.73) | EPHX2ACHECYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020437-A2 | BASIC COMPOUNDS CONTAINING TERTIARY AMIDES WITH ACTIVITY ON TACHYKININ RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2002-03-14 | — | — | WO | disclosed |