Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038315 | 1.00 | MEN1 (0.39) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL5045895 | 0.96 | TSHR (0.33) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL5045887 | 0.83 | ALDH1A1 (0.38) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL30244716 | 0.82 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL2936139 | 0.82 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL30380499 | 0.82 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL5531243 | 0.82 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL30244896 | 0.82 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL30244421 | 0.82 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL15253750 | 0.80 | MEN1 (0.34) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509968-B1 | Synthetic polycarboxylates and proteins hydrogels for drug sustained release and process for the production thereof | ISI IST SIEROVACCINOGENO ITAL (IT) | 1995-04-05 | — | — | EP | claimed |
| EP-0509968-A1 | Synthetic polycarboxylates and proteins hydrogels for drug sustained release and process for the production thereof | ISTITUTO SIEROVACCINOGENO ITALIANO I.S.I. S.p.A. (IT) | 1992-10-21 | — | — | EP | claimed |
| US-20020022585-A1 | Detergent compositions with improved whitening benefits and methods and articles employing same | THE PROCTER & GAMBLE COMPANY | 2002-02-21 | — | — | US | disclosed |
| WO-2001092451-A1 | DETERGENT COMPOSITIONS AND METHODS AND ARTICLES EMPLOYING SAME | THE PROCTER & GAMBLE COMPANY (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-0509968-B1 | Synthetic polycarboxylates and proteins hydrogels for drug sustained release and process for the production thereof | ISI IST SIEROVACCINOGENO ITAL (IT) | 1995-04-05 | — | — | EP | disclosed |
| EP-0509968-A1 | Synthetic polycarboxylates and proteins hydrogels for drug sustained release and process for the production thereof | ISTITUTO SIEROVACCINOGENO ITALIANO I.S.I. S.p.A. (IT) | 1992-10-21 | — | — | EP | disclosed |