SCHEMBL7532269

SCHEMBL7532269

C=C(C)C(=O)OC(F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
THRB P10828 1/20 0.34
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55495 1.00 ALDH1A1 (0.37) ALDH1A1THRBTSHR
SCHEMBL28207691 1.00 ALDH1A1 (0.37) ALDH1A1THRBTSHR
SCHEMBL28378224 1.00 ALDH1A1 (0.37) ALDH1A1THRBTSHR
SCHEMBL896745 1.00 ALDH1A1 (0.37) ALDH1A1THRBTSHR
SCHEMBL5086534 1.00 ALDH1A1 (0.37) ALDH1A1THRBTSHR
SCHEMBL2396171 1.00 ALDH1A1 (0.37) ALDH1A1THRBTSHR
SCHEMBL676250 1.00 ALDH1A1 (0.37) ALDH1A1THRBTSHR
Fluoride SCHEMBL28924098 0.98 ALDH1A1 (0.35) ALDH1A1THRB
SCHEMBL2400720 0.98 ALDH1A1 (0.38) ALDH1A1THRBTSHR
SCHEMBL751394 0.94 ALDH1A1 (0.38) ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0815836-B1 Oil-based solid cosmetic composition containing a fluoroalkyl (meth)acrylate copolymer and use thereof KAO CORP (JP) 2002-04-03 EP disclosed
US-5849318-A Oil-based solid cosmetic composition KAO CORPORATION (JP) 1998-12-15 US disclosed
EP-0815836-A2 Oil-based solid cosmetic composition containing a fluoroalkyl (meth)acrylate copolymer and use thereof KAO CORPORATION (JP) 1998-01-07 EP disclosed