Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15687768 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 | |
| SCHEMBL9318142 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 | |
| SCHEMBL8878248 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 | |
| SCHEMBL340114 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 | |
| SCHEMBL9544301 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 | |
| SCHEMBL7092874 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 | |
| SCHEMBL5902659 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 | |
| SCHEMBL12214087 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 | |
| SCHEMBL3095599 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 | |
| SCHEMBL12964460 | 0.97 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791589-B1 | 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENES WHICH INHIBIT LDL OXIDATION | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-5789436-A | ARTERIOSCLEROSIS; INHIBITORS OF OXIDATION OF LOW DENSITY LIPOPROTEINS; | CHUGAI SEIYAK KABUSHIKI KAISHA (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0791589-A1 | 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENES WHICH INHIBIT LDL OXIDATION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-27 | — | — | EP | disclosed |
| WO-1993016996-A1 | INDOLE DERIVATIVES AS TESTOSTERONE-5-ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-02 | — | — | WO | disclosed |