SCHEMBL7532404

SCHEMBL7532404

C[C@H]1OC(CCCCCCCCCC(=O)O)[C@@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.40
LMNA P02545 1/20 0.40
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
IGF2R P11717 1/20 0.40
PPARG P37231 7/20 0.40
ABL1 P00519 1/20 0.40
IDE P14735 1/20 0.40
RIN1 Q13671 1/20 0.40
NR2E3 Q9Y5X4 1/20 0.40
NCOR2 Q9Y618 1/20 0.40
SELP P16109 1/20 0.39
GPR84 Q9NQS5 7/20 0.38
PPARD Q03181 6/20 0.38
PPARA Q07869 6/20 0.38
HDAC11 Q96DB2 5/20 0.38
ALDH1A1 P00352 2/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5193552 0.86 TSHR (0.50) TSHRLMNANFKB1PMP22PPARG
SCHEMBL9814457 0.81 IGF2R (0.44) TSHRLMNANFKB1PMP22IGF2R
SCHEMBL8405222 0.81 IGF2R (0.44) TSHRLMNANFKB1PMP22IGF2R
SCHEMBL8429129 0.81 IGF2R (0.44) TSHRLMNANFKB1PMP22IGF2R
SCHEMBL8427112 0.81 IGF2R (0.44) TSHRLMNANFKB1PMP22IGF2R
SCHEMBL8429127 0.81 IGF2R (0.44) TSHRLMNANFKB1PMP22IGF2R
SCHEMBL8907380 0.81 IGF2R (0.44) TSHRLMNANFKB1PMP22IGF2R
SCHEMBL10620442 0.81 IGF2R (0.44) TSHRLMNANFKB1PMP22IGF2R
SCHEMBL10623070 0.81 IGF2R (0.44) TSHRLMNANFKB1PMP22IGF2R
SCHEMBL2530868 0.81 IGF2R (0.44) TSHRLMNANFKB1PMP22IGF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63253025-A None JP disclosed
EP-0771191-B1 IMMUNOLOGICAL ACTIVITY OF RHAMNOLIPIDS PILJAC GORAN (US) 2002-04-10 EP disclosed
EP-0771191-A4 IMMUNOLOGICAL ACTIVITY OF RHAMNOLIPIDS PILJAC GORAN (US) 1998-10-07 EP disclosed
EP-0771191-A1 IMMUNOLOGICAL ACTIVITY OF RHAMNOLIPIDS Piljac, Goran (US) 1997-05-07 EP disclosed
US-5514661-A AUTOIMMUNE DISEASE TREATMENT PARADIGM BIOMEDICAL, INC. 1996-05-07 US disclosed
WO-1996002233-A1 IMMUNOLOGICAL ACTIVITY OF RHAMNOLIPIDS PILJAC GORAN (US) 1996-02-01 WO disclosed
US-5466675-A Autoimmune diseases PARADIGM BIOMEDICAL, INC. 1995-11-14 US disclosed
JP-S63253025-A PHOSPHOLIPASE A2 INHIBITOR YAMANOUCHI PHARMACEUT CO LTD 1988-10-20 JP disclosed