SCHEMBL7532640

SCHEMBL7532640

[CH2]C(CCCC)C1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.43
CYP1A2 P05177 1/20 0.41
SIGMAR1 Q99720 3/20 0.36
MMP1 P03956 1/20 0.34
MMP7 P09237 1/20 0.34
MMP12 P39900 1/20 0.34
ECE1 P42892 1/20 0.34
MMP13 P45452 1/20 0.34
EPHX1 P07099 10/20 0.33
TSHR P16473 1/20 0.33
EPHX2 P34913 2/20 0.33
METAP1 P53582 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5504178 1.00 SHBG (0.43) SHBGCYP1A2SIGMAR1MMP1MMP7
SCHEMBL1524748 0.98 SHBG (0.39) SHBGCYP1A2SIGMAR1MMP1MMP7
SCHEMBL28319985 0.94 SHBG (0.41) SHBGCYP1A2SIGMAR1EPHX1TSHR
SCHEMBL27450259 0.93 SHBG (0.34) SHBGCYP1A2SIGMAR1EPHX1METAP1
SCHEMBL1524836 0.92 SHBG (0.40) SHBGCYP1A2SIGMAR1EPHX1TSHR
SCHEMBL9209093 0.92 SHBG (0.40) SHBGCYP1A2SIGMAR1EPHX1TSHR
SCHEMBL9206222 0.89 SHBG (0.37) SHBGCYP1A2SIGMAR1EPHX1TSHR
SCHEMBL9204414 0.89 SHBG (0.37) SHBGCYP1A2SIGMAR1EPHX1TSHR
SCHEMBL9205033 0.89 SHBG (0.37) SHBGCYP1A2SIGMAR1EPHX1TSHR
SCHEMBL6719652 0.89 SHBG (0.37) SHBGCYP1A2SIGMAR1EPHX1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107641136-A Two organic group phosphinates, Its Preparation Method And Use 科莱恩塑料和涂料有限公司 2018-01-30 CN claimed
EP-3423530-A1 ELECTRON BEAM CURABLE INKJET INK COMPOSITION Inx International Ink Co. (US) 2019-01-09 EP disclosed
CN-107828207-A Fire retardant combination of stabilizers for thermoplastic polymer 科莱恩塑料和涂料有限公司 2018-03-23 CN disclosed
CN-1361759-A 6-hydroxy-2-naphthyl carbinol and process for producing the same MITSUBISHI CHEM CORP (JP) 2002-07-31 CN disclosed
EP-1008429-B1 Paintable organopolysiloxane mold release compositions WACKER CHEMIE GMBH (DE) 2002-04-03 EP disclosed
EP-1186588-A1 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2002-03-13 EP disclosed
US-6294007-B1 STABILITY WACKER SILICONES CORPORATION 2001-09-25 US disclosed
EP-1008429-A1 Paintable organopolysiloxane mold release compositions and processes for their use Wacker-Chemie GmbH (DE) 2000-06-14 EP disclosed
EP-0421441-B1 Pantothenic acid derivatives FUJIREBIO KK (JP) 1995-01-25 EP disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 EP disclosed
EP-0086826-A4 ALPHA-BRANCHED ALKYLTHIOPHOSPHATE PESTICIDES. FMC CORP (US) 1983-12-23 EP disclosed
EP-0086826-A1 ALPHA-BRANCHED ALKYLTHIOPHOSPHATE PESTICIDES. FMC CORP (US) 1983-08-31 EP disclosed
WO-1983000870-A1 ALPHA-BRANCHED ALKYLTHIOPHOSPHATE PESTICIDES FMC CORP (US) 1983-03-17 WO disclosed