Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925862 | 0.77 | SLC6A4 (0.37) | BACE1BACE2SLC6A2SLC6A4OPRM1 | |
| SCHEMBL10726987 | 0.76 | SLC6A4 (0.38) | BACE1BACE2SLC6A2SLC6A4OPRM1 | |
| SCHEMBL28002157 | 0.74 | SLC6A4 (0.47) | SLC6A2SLC6A4OPRM1 | |
| SCHEMBL31314377 | 0.74 | CYP1A2 (0.41) | — | |
| SCHEMBL28169087 | 0.73 | CYP1A2 (0.39) | — | |
| SCHEMBL28562635 | 0.73 | OPRM1 (0.40) | BACE1BACE2SLC6A2SLC6A4OPRM1 | |
| SCHEMBL547417 | 0.72 | OPRM1 (0.41) | SLC6A2SLC6A4OPRM1 | |
| SCHEMBL547562 | 0.72 | OPRM1 (0.41) | SLC6A2SLC6A4OPRM1 | |
| SCHEMBL23595697 | 0.71 | — | — | |
| SCHEMBL24925663 | 0.71 | TDP1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5239110-A | Phenylcyclohexanol derivatives as agents for treating CNS disorders | STERLING WINTHROP, INC. (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0063793-A2 | (Arylmethyl)aryl-amino-cyclohexanols, -cyclohexanes, -cyclohexenes and intermediates thereof, a process for preparing the same and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-11-03 | — | — | EP | disclosed |
| US-4313959-A | (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-02-02 | — | — | US | disclosed |
| US-4313959-A | (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-02-02 | — | — | US | disclosed |