Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 5/20 | 0.59 |
| ▸ | TTK | P33981 | 6/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.50 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.50 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.50 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 6/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377947 | 0.85 | MAP2K4 (0.63) | MAP2K4TTKMAPK8MAPK1MAPKAPK2 | |
| SCHEMBL12073910 | 0.84 | TTK (0.65) | MAP2K4TTKMAPK8MAPK1MAPKAPK2 | |
| SCHEMBL5785886 | 0.83 | AURKA (0.66) | MAP2K4TTKMAPK8MAPK1MAPKAPK2 | |
| SCHEMBL5374481 | 0.80 | MAP2K4 (0.67) | MAP2K4TTKMAPK8MAPK1MAPKAPK2 | |
| SCHEMBL5381639 | 0.80 | AAK1 (0.59) | MAP2K4TTKMAPK8AURKAMAP2K7 | |
| SCHEMBL5372815 | 0.79 | MAP2K4 (0.56) | MAP2K4TTKMAPK8MAPK1MAPKAPK2 | |
| SCHEMBL5399319 | 0.79 | AURKA (0.56) | MAP2K4TTKMAPK8MAPKAPK2AURKA | |
| SCHEMBL5799264 | 0.79 | AURKA (0.69) | MAP2K4TTKAURKAMAP2K7CSNK1D | |
| SCHEMBL5783999 | 0.79 | AURKA (0.57) | MAP2K4TTKMAPK8MAPK1MAPKAPK2 | |
| SCHEMBL14514461 | 0.79 | AURKA (0.54) | MAP2K4TTKMAPK8MAPK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103229-A1 | Indazole derivatives as JNK inhibitors and compositions and methods related thereto | SIGNAL PHARMACEUTICALS, LLC | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103229-A1 | Indazole derivatives as JNK inhibitors and compositions and methods related thereto | MAP3K7, MAP3K1, MAP3K8 | MAP2K4 71/4885TTK 476/4885MAPK8 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.