Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051337 | 0.87 | SMN1; SMN2 (0.70) | MAPTL3MBTL1SMN1; SMN2ALDH1A1KMT2A | |
| Ethyne SCHEMBL8050785 | 0.82 | SMN1; SMN2 (0.64) | MAPTL3MBTL1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2677861 | 0.82 | HSD17B3 (0.67) | L3MBTL1SMN1; SMN2PARP10PARP4PARP1 | |
| SCHEMBL221282 | 0.81 | MAPT (0.57) | MAPTL3MBTL1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10389933 | 0.80 | SMN1; SMN2 (0.83) | MAPTL3MBTL1SMN1; SMN2ALDH1A1KMT2A | |
| Terephthalamide SCHEMBL23774 | 0.79 | PARP1 (0.71) | MAPTL3MBTL1SMN1; SMN2PARP10PARP4 | |
| SCHEMBL31042968 | 0.79 | CA2 (0.55) | MAPTL3MBTL1SMN1; SMN2CA2ALDH1A1 | |
| SCHEMBL9448618 | 0.79 | PARP1 (0.57) | MAPTL3MBTL1SMN1; SMN2PARP10PARP1 | |
| SCHEMBL8282094 | 0.78 | MAPT (0.59) | MAPTL3MBTL1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2644065 | 0.78 | SMN1; SMN2 (0.59) | MAPTL3MBTL1SMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| US-20100256755-A1 | Poly(Tetrafluoroethene) Polymer With Nitric Oxide Donating Surface | MEDTRONIC VASCULAR, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |
| CN-1336919-A | Phenylphenanthridines with PDE-IV inhibiting activity | BYK GULDEN LOMBERG CHEM FAB (DE) | 2002-02-20 | — | — | CN | disclosed |