Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 6/20 | 0.73 |
| ▸ | CCR8 | P51685 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195397 | 0.89 | STS (0.58) | STSCCR8SFRP1HTTNPC1 | |
| SCHEMBL2961651 | 0.89 | MMP13 (0.62) | STSCCR8NR1H2SFRP1ALDH1A1 | |
| SCHEMBL4602370 | 0.88 | MMP13 (0.63) | STSCCR8NR1H2SFRP1GPR119 | |
| SCHEMBL3413300 | 0.88 | STS (0.57) | STSCCR8SFRP1HTTALDH1A1 | |
| SCHEMBL24169967 | 0.87 | CCR8 (0.57) | STSCCR8SFRP1GPR119MMP13 | |
| SCHEMBL17729016 | 0.86 | STS (0.62) | STSNR1H2SFRP1MMP13BRD4 | |
| SCHEMBL21292730 | 0.86 | STS (0.55) | STSCCR8SFRP1ALDH1A1GPR119 | |
| SCHEMBL15504588 | 0.86 | STS (0.55) | STSCCR8NR1H2SFRP1ALDH1A1 | |
| SCHEMBL21292735 | 0.86 | STS (0.55) | STSCCR8SFRP1GPR119MMP13 | |
| SCHEMBL21292864 | 0.86 | STS (0.57) | STSCCR8SFRP1ALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1190710-A1 | PREVENTIVE OR THERAPEUTIC DRUGS FOR DIABETES | SHIONOGI & CO., LTD. (JP) | 2002-03-27 | — | — | EP | disclosed |