Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089557 | 0.96 | NPC1 (0.59) | NPC1RAB9AFAAHTSHRLTA4H | |
| SCHEMBL8957600 | 0.95 | NPC1 (0.58) | NPC1RAB9AFAAHTSHRNR5A1 | |
| SCHEMBL10563388 | 0.95 | NPC1 (0.58) | NPC1RAB9AFAAHTSHRNR5A1 | |
| SCHEMBL7525722 | 0.95 | NPC1 (0.58) | NPC1RAB9AFAAHTSHRNR5A1 | |
| SCHEMBL8006745 | 0.95 | NPC1 (0.58) | NPC1RAB9AFAAHTSHRNR5A1 | |
| SCHEMBL2200281 | 0.95 | NPC1 (0.58) | NPC1RAB9AFAAHTSHRNR5A1 | |
| SCHEMBL2089955 | 0.95 | NPC1 (0.58) | NPC1RAB9AFAAHTSHRNR5A1 | |
| SCHEMBL5948125 | 0.95 | NPC1 (0.58) | NPC1RAB9AFAAHTSHRNR5A1 | |
| SCHEMBL9101286 | 0.93 | MAPT (0.49) | NPC1RAB9AFAAHCA12CA1 | |
| SCHEMBL5637694 | 0.85 | NQO1 (0.56) | NPC1TSHRGAACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |
| EP-0318759-B1 | MULTILAYERED ELECTROPHOTOGRAPHICAL RECORDING MATERIAL | BASF Aktiengesellschaft (DE) | 1993-01-27 | — | — | EP | disclosed |
| US-5069991-A | NAPHTHOLACTAM OR ISINDOLENINE DYE | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| US-4971957-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, BENZENECARBOXAMIDOPHOSPHONATES OR BENZENETHIOCARBOXAMIDOPHOSPHONATES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4924003-A | Pyrazoline compounds | BASF AKTIENGESELLSCHAFT (DE) | 1990-05-08 | — | — | US | disclosed |
| US-4883732-A | Method of forming printing plate using isoindolenine deratives | BASF AKTIENGESELLSCHAFT (DE) | 1989-11-28 | — | — | US | disclosed |
| US-4880718-A | AS PHOTOSENSITIZERS AND CHARGE GENERATING COMPOUNDS; OFFSET PRINTING PLATES, COPIERS, PHOTORESISTS MADE USING LASERS; HIGH CONTRAST AND VOLTAGE | BASF AKTIENGESELLSCHAFT (DE) | 1989-11-14 | — | — | US | disclosed |
| US-4373102-A | Isoindoline dyes, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1983-02-08 | — | — | US | disclosed |
| EP-0017132-B1 | DYESTUFFS, THEIR PREPARATION AND UTILISATION | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0017132-A1 | Dyestuffs, their preparation and utilisation | BASF Aktiengesellschaft (DE) | 1980-10-15 | — | — | EP | disclosed |