Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | RXRA | P19793 | 2/20 | 0.65 |
| ▸ | HMGCR | P04035 | 2/20 | 0.65 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257547 | 0.93 | NR4A2 (0.65) | NR1I2NR4A2PDE4DRXRAHMGCR | |
| SCHEMBL4911326 | 0.91 | NR4A2 (0.71) | NR1I2NR4A2PDE4DRXRAHMGCR | |
| SCHEMBL4911333 | 0.91 | NR4A2 (0.71) | NR1I2NR4A2PDE4DRXRAHMGCR | |
| SCHEMBL30881627 | 0.89 | NR4A2 (0.80) | NR1I2NR4A2PDE4DRXRAHMGCR | |
| SCHEMBL30291805 | 0.89 | NR4A2 (0.80) | NR1I2NR4A2PDE4DRXRAHMGCR | |
| SCHEMBL30203740 | 0.89 | NR4A2 (0.80) | NR1I2NR4A2PDE4DRXRAHMGCR | |
| SCHEMBL14273684 | 0.89 | NR4A2 (0.80) | NR1I2NR4A2PDE4DRXRAHMGCR | |
| SCHEMBL1582437 | 0.89 | NR4A2 (0.80) | NR1I2NR4A2PDE4DRXRAHMGCR | |
| SCHEMBL2904607 | 0.89 | NR4A2 (0.80) | NR1I2NR4A2PDE4DRXRAHMGCR | |
| SCHEMBL10153166 | 0.89 | NR4A2 (0.80) | NR1I2NR4A2PDE4DRXRAHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747341-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE MEVALONOLACTONE COMPOUNDS | DAICEL CHEM (JP) | 2002-05-22 | — | — | EP | disclosed |
| EP-0747341-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE MEVALONOLACTONE COMPOUND | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |