Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | RXRA | P19793 | 3/20 | 0.63 |
| ▸ | HMGCR | P04035 | 3/20 | 0.63 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.35 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533702 | 0.93 | NR1I2 (0.68) | NR4A2PDE4DNR1I2RXRAHMGCR | |
| SCHEMBL10073658 | 0.91 | NR4A2 (0.75) | NR4A2PDE4DNR1I2RXRAHMGCR | |
| SCHEMBL4911333 | 0.84 | NR4A2 (0.71) | NR4A2PDE4DNR1I2RXRAHMGCR | |
| SCHEMBL4911326 | 0.84 | NR4A2 (0.71) | NR4A2PDE4DNR1I2RXRAHMGCR | |
| SCHEMBL2898752 | 0.83 | NR4A2 (0.80) | NR4A2PDE4DNR1I2RXRAHMGCR | |
| SCHEMBL14273684 | 0.83 | NR4A2 (0.80) | NR4A2PDE4DNR1I2RXRAHMGCR | |
| SCHEMBL3529615 | 0.83 | NR4A2 (0.80) | NR4A2PDE4DNR1I2RXRAHMGCR | |
| SCHEMBL14262755 | 0.83 | NR4A2 (0.80) | NR4A2PDE4DNR1I2RXRAHMGCR | |
| SCHEMBL13776436 | 0.81 | NR4A2 (0.75) | NR4A2PDE4DNR1I2RXRAHMGCR | |
| SCHEMBL13991559 | 0.81 | NR4A2 (0.77) | NR4A2PDE4DNR1I2RXRAHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010089770-A2 | IMPROVED PROCESS FOR THE PREPARATION OF HIGHLY PURE (3R,5S)-7-[2-CYCLOPROPYL-4-(4-FLUOROPHENYL) QUINOLIN-3-YL]-3,5-DIHYDROXY-6(E)-HEPTENOIC ACID AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | MSN LABORATORIES LIMITED (IN) | 2010-08-12 | — | — | WO | disclosed |