SCHEMBL7533882

SCHEMBL7533882

CCC(C)(C)c1ccc(OCCCC(=O)Cl)c(C(C)(C)CC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 9/20 0.60
MAPK1 P28482 5/20 0.60
NPSR1 Q6W5P4 5/20 0.60
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
ALDH1A1 P00352 3/20 0.60
MAPT P10636 4/20 0.55
HTT P42858 3/20 0.55
UBE2N P61088 2/20 0.55
GLA P06280 1/20 0.55
MITF O75030 1/20 0.55
RAB9A P51151 3/20 0.50
RAD52 P43351 2/20 0.50
STAT3 P40763 1/20 0.50
RCE1 Q9Y256 1/20 0.50
APAF1 O14727 1/20 0.50
HSP90AA1 P07900 1/20 0.50
NOD2 Q9HC29 1/20 0.50
RRM1 P23921 1/20 0.42
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9588598 0.95 SMN1; SMN2 (0.57) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL1285803 0.88 MAPK1 (0.61) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL12548316 0.88 MAPK1 (0.61) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL4477633 0.88 MAPK1 (0.61) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL4477630 0.87 MAPK1 (0.60) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL4804002 0.85 MAPK1 (0.71) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL7767137 0.82 MAPK1 (0.61) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL7767139 0.82 MAPK1 (0.61) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL9769466 0.82 MAPK1 (0.64) SMN1; SMN2MAPK1NPSR1MEN1KMT2A
SCHEMBL9083094 0.82 MAPK1 (0.64) SMN1; SMN2MAPK1NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882011-B1 PROCESS FOR PREPARING N-(3-AMINO-4-CHLOROPHENYL) ACYLAMIDES EASTMAN CHEM CO (US) 2002-03-27 EP disclosed
EP-0601642-B1 Photographic silver halide material and process EASTMAN KODAK CO (US) 1999-09-01 EP disclosed
EP-0882011-A1 PROCESS FOR PREPARING N-(3-AMINO-4-CHLOROPHENYL) ACYLAMIDES EASTMAN CHEMICAL COMPANY (US) 1998-12-09 EP disclosed
EP-0551509-B1 PHOTOGRAPHIC MATERIAL AND PROCESS EASTMAN KODAK CO (US) 1998-03-18 EP disclosed
US-5663434-A AMIDATION, SULFONAMIDATION, INTERMEDIATES FOR COLOR COUPLERS EASTMAN CHEMICAL COMPANY (US) 1997-09-02 US disclosed
WO-1997027171-A1 PROCESS FOR PREPARING N-(3-AMINO-4-CHLOROPHENYL) ACYLAMIDES EASTMAN CHEMICAL COMPANY (US) 1997-07-31 WO disclosed
US-5364753-A Mixture of magenta and colored couplers, improved image durability KONICA CORPORATION (JP) 1994-11-15 US disclosed
EP-0601642-A1 Photographic silver halide material and process EASTMAN KODAK COMPANY (US) 1994-06-15 EP disclosed
US-5306604-A Dispersibility, low melting points EASTMAN KODAK COMPANY (US) 1994-04-26 US disclosed
US-5275926-A Photosensitivity, antifogging and resistance to formaldehyde KONICA CORPORATION (JP) 1994-01-04 US disclosed
EP-0219087-A2 Light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1987-04-22 EP disclosed
EP-0087388-B1 PYRAZOLONE COUPLERS AND COLOUR PHOTOGRAPHIC SILVER HALIDE RECORDING MATERIAL CONTAINING THEM CIBA-GEIGY AG (CH) 1986-06-25 EP disclosed
US-4581326-A PYRROLOTRIAZOLE MAGENTA COUPLER AND NON-COLOR FORMING PHENOL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-08 US disclosed
US-4562146-A HIGHLY DISPERSION-STABLE MAGENTA COUPLER AND PHENOLIC COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-12-31 US disclosed
US-4370499-A CHEMICAL INTERMEDIATES FOR COLOR PHOTOGRAPHY BAYER AKTIENGESELLSCHAFT (DE) 1983-01-25 US disclosed
US-4250251-A COUPLER SOLVENT PARTICLES FOR FORMING A MICROCRYSTALLINE DYE HAVING BROADENED INFRARED ABSORPTION SPECTRA EASTMAN KODAK COMPANY (US) 1981-02-10 US disclosed
US-4198239-A ACYLAMINO SUBSTITUTED HYDROQUINONES AGFA-GEVAERT, A.G. (DE) 1980-04-15 US disclosed
US-4175968-A N-ACYL-AMINOPYRICATECHOL COMPOUNDS AGFA-GEVAERT, A.G. (DE) 1979-11-27 US disclosed
US-4146396-A TWO EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1979-03-27 US disclosed
US-4106942-A COMPOUNDS CONTAINING SULFIDE, KETONE, AND AMIDE GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1978-08-15 US disclosed