SCHEMBL4477633

SCHEMBL4477633

CCC(C)(C)c1ccc(OCCCC(N)=O)c(C(C)(C)CC)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.61
NPSR1 Q6W5P4 5/20 0.61
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
ALDH1A1 P00352 1/20 0.61
MAPT P10636 4/20 0.56
HTT P42858 3/20 0.56
UBE2N P61088 2/20 0.56
GLA P06280 1/20 0.56
MITF O75030 1/20 0.56
RAD52 P43351 2/20 0.51
STAT3 P40763 1/20 0.51
RCE1 Q9Y256 1/20 0.51
APAF1 O14727 1/20 0.51
HSP90AA1 P07900 1/20 0.51
RAB9A P51151 1/20 0.51
NOD2 Q9HC29 1/20 0.51
RRM1 P23921 1/20 0.42
HDAC6 Q9UBN7 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1285803 0.89 MAPK1 (0.61) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL12548316 0.89 MAPK1 (0.61) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL4477630 0.88 MAPK1 (0.60) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL7533882 0.88 SMN1; SMN2 (0.60) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL1061587 0.86 MAPK1 (0.71) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL9171751 0.85 MAPK1 (0.56) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL9353082 0.85 MAPK1 (0.56) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL9469370 0.84 MAPK1 (0.55) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL9588598 0.83 SMN1; SMN2 (0.57) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL7767139 0.83 MAPK1 (0.61) MAPK1NPSR1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530039-A1 Light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1993-03-03 EP claimed
US-4308343-A MAGENTA 2-EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US claimed
US-7531298-B2 Silver halide color photosensitive material FUJIFILM CORPORATION (JP) 2009-05-12 US disclosed
US-20050106513-A1 Blue, green, red-sensitive layer and a non-light-sensitive layer on a support and a silver halide color photosensitive material of a fluorinated diester metal salt; capable of undergoing a one-electron oxidation to a one-electron oxidation product capable of releasing electrons and forming a bond FUJI PHOTO FILM CO., LTD. 2005-05-19 US disclosed
EP-0355818-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-05-10 EP disclosed
EP-0276319-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO LTD (JP) 1994-10-05 EP disclosed
EP-0285176-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-06-08 EP disclosed
US-5275926-A Photosensitivity, antifogging and resistance to formaldehyde KONICA CORPORATION (JP) 1994-01-04 US disclosed
EP-0304067-B1 Silver halide color photographic light-sensitive material containing epoxy compound FUJI PHOTO FILM CO LTD (JP) 1993-11-10 EP disclosed
US-5238797-A SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL CONTAINING A 1-PENTAHALOGENOPHENYL-SUBSTITUTED 5-PYRAZOLONE COLORED MAGENTA COUPLER KONICA CORPORATION (JP) 1993-08-24 US disclosed
EP-0304810-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1993-07-14 EP disclosed
EP-0067689-B1 CYAN COUPLERS AND COLOUR PHOTOGRAPHIC MATERIALS CONTAINING THEM KONICA CORPORATION (JP) 1986-09-10 EP disclosed
US-4554244-A PHENOL TYPE CYAN COUPLER WITH UREA GROUP KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-11-19 US disclosed
US-4465766-A Silver halide photosensitive materials for color photography KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-08-14 US disclosed
US-4451559-A 2-(SUBSTITUTED PHENYL-UREIDO) PHENOL-TYPE CYAN COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-05-29 US disclosed
EP-0067689-A1 Cyan couplers and colour photographic materials containing them KONICA CORPORATION (JP) 1982-12-22 EP disclosed
US-4308343-A MAGENTA 2-EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US disclosed
US-4200466-A Light-sensitive silver halide photographic materials KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-04-29 US disclosed
US-4171975-A MAGENTA COUPLER AND AN AMIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-10-23 US disclosed
US-4146396-A TWO EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1979-03-27 US disclosed