Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.30 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.30 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756042 | 0.87 | NR3C2 (0.55) | NR3C2ALDH1A1KDM4ERCE1EPHX2 | |
| SCHEMBL756053 | 0.85 | NR3C2 (0.51) | NR3C2EPHX2NR1H4 | |
| SCHEMBL753817 | 0.84 | NR3C2 (0.43) | NR3C2ALDH1A1EPHX2NR1H4SLC16A3 | |
| SCHEMBL755980 | 0.80 | NR3C2 (0.56) | NR3C2ALDH1A1MEN1KMT2A | |
| SCHEMBL756283 | 0.79 | NR3C2 (0.53) | NR3C2 | |
| SCHEMBL754681 | 0.78 | NR3C2 (0.53) | NR3C2MCHR1MEN1KMT2A | |
| SCHEMBL754215 | 0.78 | NR3C2 (0.61) | NR3C2ALDH1A1 | |
| SCHEMBL754664 | 0.77 | NR3C2 (0.59) | NR3C2EPHX2KCNH2 | |
| SCHEMBL755391 | 0.76 | NR3C2 (0.72) | NR3C2MEN1KMT2AKCNH2 | |
| SCHEMBL756893 | 0.74 | NR3C2 (0.55) | NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984345-B9 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | claimed |
| EP-1984345-B1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-08-31 | — | — | EP | claimed |