Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.44 |
| ▸ | CEL | P19835 | 2/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857686 | 0.91 | TSHR (0.55) | TSHRALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10790290 | 0.86 | ACMSD (0.50) | ACMSDKMOPTGDR2ALDH1A1TAS1R3 | |
| SCHEMBL31011018 | 0.86 | ACMSD (0.50) | ACMSDKMOPTGDR2ALDH1A1TAS1R3 | |
| SCHEMBL9403931 | 0.86 | ACMSD (0.50) | ACMSDKMOPTGDR2ALDH1A1TAS1R3 | |
| SCHEMBL300805 | 0.86 | ACMSD (0.50) | ACMSDKMOPTGDR2ALDH1A1TAS1R3 | |
| SCHEMBL10790137 | 0.86 | ACMSD (0.50) | ACMSDKMOPTGDR2ALDH1A1TAS1R3 | |
| SCHEMBL11595517 | 0.85 | ACMSD (0.49) | ACMSDKMOPTGDR2ALDH1A1TAS1R3 | |
| SCHEMBL10790315 | 0.84 | ACMSD (0.49) | ACMSDKMOPTGDR2ALDH1A1TAS1R3 | |
| SCHEMBL30730923 | 0.82 | PTGDR2 (0.53) | ACMSDKMOPTGDR2ALDH1A1SLC6A2 | |
| SCHEMBL50486 | 0.82 | PTGDR2 (0.53) | ACMSDKMOPTGDR2ALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192196-A1 | PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS | EASTMAN CHEMICAL COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1159315-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000075204-A1 | PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS | EASTMAN CHEMICAL COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-2000052068-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |