Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321602 | 0.85 | GRM5 (0.46) | GRM5CYP2D6CA2MAPTKDM4E | |
| SCHEMBL7527637 | 0.85 | GRM5 (0.46) | GRM5CYP2D6CA2MAPTKDM4E | |
| SCHEMBL11546959 | 0.82 | CYP2D6 (0.46) | GRM5CYP2D6CA2MAPTKDM4E | |
| SCHEMBL18012037 | 0.78 | CYP2D6 (0.59) | GRM5CYP2D6POLBLMNASLC6A3 | |
| SCHEMBL4681142 | 0.78 | CYP2D6 (0.59) | GRM5CYP2D6POLBLMNASLC6A3 | |
| SCHEMBL1443275 | 0.73 | GRM5 (0.66) | GRM5CYP2D6CA2 | |
| SCHEMBL13067504 | 0.73 | GRM5 (0.66) | GRM5CYP2D6CA2 | |
| SCHEMBL2798313 | 0.73 | GRM5 (0.66) | GRM5CYP2D6CA2 | |
| SCHEMBL3988577 | 0.73 | GRM5 (0.66) | GRM5CYP2D6CA2 | |
| SCHEMBL14508491 | 0.73 | GRM5 (0.66) | GRM5CYP2D6CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844233-B1 | Process for preparing alpha-amino acid amides, alpha-amino acids and derivatives thereof | DSM NV (NL) | 2002-04-03 | — | — | EP | claimed |
| US-5977406-A | Process for preparing α-amino acid amides, α-amino acids and derivatives thereof | DSM NV (NL) | 1999-11-02 | — | — | US | claimed |
| EP-0844233-A1 | Process for preparing alpha-amino acid amides, alpha-amino acids and derivatives thereof | DSM N.V. (NL) | 1998-05-27 | — | — | EP | claimed |
| EP-0844233-B1 | Process for preparing alpha-amino acid amides, alpha-amino acids and derivatives thereof | DSM NV (NL) | 2002-04-03 | — | — | EP | disclosed |
| US-5977406-A | Process for preparing α-amino acid amides, α-amino acids and derivatives thereof | DSM NV (NL) | 1999-11-02 | — | — | US | disclosed |
| EP-0844233-A1 | Process for preparing alpha-amino acid amides, alpha-amino acids and derivatives thereof | DSM N.V. (NL) | 1998-05-27 | — | — | EP | disclosed |