Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TST | Q16762 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531754 | 1.00 | HTR2A (0.54) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7530888 | 1.00 | HTR2A (0.54) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL13908985 | 1.00 | HTR2A (0.54) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL31029907 | 1.00 | HTR2A (0.54) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7535797 | 1.00 | HTR2A (0.54) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL15656900 | 0.92 | HSD11B1 (0.49) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL127209 | 0.92 | ESR1 (0.61) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11204739 | 0.92 | ESR1 (0.61) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6288820 | 0.92 | ESR1 (0.61) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7528403 | 0.92 | ESR1 (0.61) | HTR2AESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937094-B1 | METHOD FOR THE PRODUCTION OF IVERMECTIN | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| US-6072052-A | REACTING MIXTURES OF AVERMECTIN B1A AND B1B WITH HYDROGENATION CATALYST IN A REACTION SOLVENT TO PRODUCE IVERMECTIN, REMOVING REACTION SOLVENT, THEN REMOVING CATALYST USING LIPOPHILIC SOLVENT EXTRACTION | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-06 | — | — | US | disclosed |