Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | FLT4 | P35916 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121241 | 0.87 | BDKRB1 (0.41) | P2RX7POLBPTPN7DUSP3BDKRB1 | |
| SCHEMBL764453 | 0.84 | BDKRB1 (0.41) | P2RX7POLBBDKRB1PDGFRBFLT4 | |
| SCHEMBL765183 | 0.83 | BDKRB1 (0.40) | P2RX7POLBBDKRB1MAPTEPHX2 | |
| SCHEMBL12238932 | 0.82 | L3MBTL1 (0.43) | P2RX7POLBPTPN7DUSP3BDKRB1 | |
| SCHEMBL765666 | 0.81 | BDKRB1 (0.43) | P2RX7POLBPTPN7DUSP3BDKRB1 | |
| SCHEMBL764436 | 0.81 | BDKRB1 (0.41) | P2RX7POLBPTPN7DUSP3BDKRB1 | |
| SCHEMBL10121227 | 0.80 | EPHX2 (0.44) | P2RX7PTPN7DUSP3EPHX2L3MBTL1 | |
| SCHEMBL764477 | 0.80 | L3MBTL1 (0.41) | P2RX7POLBPTPN7DUSP3BDKRB1 | |
| SCHEMBL2788425 | 0.80 | EPHX2 (0.41) | P2RX7POLBPTPN7DUSP3BDKRB1 | |
| SCHEMBL12238931 | 0.80 | EPHX2 (0.53) | PTPN7DUSP3BDKRB1EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |