Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 4/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872360 | 1.00 | MEN1 (0.55) | MEN1KMT2AMMP9MMP2HPGD | |
| SCHEMBL4870057 | 0.81 | HPGD (0.59) | MEN1KMT2AHPGDPKMHTT | |
| SCHEMBL6450715 | 0.78 | MEN1 (0.63) | MEN1KMT2AHPGDPKMHTT | |
| SCHEMBL6450720 | 0.78 | MEN1 (0.63) | MEN1KMT2AHPGDPKMHTT | |
| Hydrochloric Acid SCHEMBL4871153 | 0.77 | MEN1 (0.62) | MEN1KMT2AHPGDPKMHTT | |
| SCHEMBL4864524 | 0.77 | MEN1 (0.56) | MEN1KMT2AHPGDPKMHTT | |
| SCHEMBL4912638 | 0.76 | MEN1 (0.52) | MEN1KMT2AHPGDPKMHTT | |
| SCHEMBL4867428 | 0.75 | MEN1 (0.51) | MEN1KMT2AHPGDPKMHTT | |
| SCHEMBL15251807 | 0.74 | MMP2 (0.70) | MEN1KMT2AMMP9MMP2ALDH1A1 | |
| SCHEMBL6561338 | 0.74 | MMP2 (0.70) | MEN1KMT2AMMP9MMP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254901-A1 | NITROGEN-CONTAINING 5-MEMBERED CYCLIC COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-06 | — | — | EP | claimed |