SCHEMBL7534933

SCHEMBL7534933

CC(N1Cc2ccccc2CC1Cn1cncc1Cc1ccc(C#N)cc1)S(C)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 19/20 0.44
FNTB P49356 19/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7534925 0.82 FNTA (0.46) FNTAFNTB
SCHEMBL7534652 0.81 FNTA (0.45) FNTAFNTB
SCHEMBL7582240 0.76 FNTA (0.45) FNTAFNTB
SCHEMBL7533369 0.73 FNTA (0.58) FNTAFNTB
SCHEMBL7533374 0.73 FNTA (0.58) FNTAFNTB
SCHEMBL7480291 0.73 FNTA (0.52) FNTAFNTB
SCHEMBL7480297 0.73 FNTA (0.52) FNTAFNTB
SCHEMBL7537110 0.73 FNTA (0.44) FNTAFNTB
SCHEMBL7537123 0.73 FNTA (0.44) FNTAFNTB
SCHEMBL7535976 0.72 FNTA (0.51) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1045844-A4 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 2002-08-21 EP claimed
EP-1045844-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 2000-10-25 EP claimed
WO-1999028314-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1999-06-10 WO claimed
EP-1045844-A4 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 2002-08-21 EP disclosed
EP-1045844-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 2000-10-25 EP disclosed
WO-1999028314-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1999-06-10 WO disclosed