Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.51 |
| ▸ | FNTB | P49356 | 17/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481387 | 1.00 | FNTA (0.51) | FNTAFNTBPGGT1BNR1D1CYP11B1 | |
| SCHEMBL7480291 | 0.89 | FNTA (0.52) | FNTAFNTBPGGT1BNR1D1 | |
| SCHEMBL7480297 | 0.89 | FNTA (0.52) | FNTAFNTBPGGT1BNR1D1 | |
| SCHEMBL7473823 | 0.76 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL7533374 | 0.73 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL7533369 | 0.73 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL7534933 | 0.72 | FNTA (0.44) | FNTAFNTB | |
| SCHEMBL7534925 | 0.72 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL7582240 | 0.71 | FNTA (0.45) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL7537123 | 0.68 | FNTA (0.44) | FNTAFNTBCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045844-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-1045844-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999028314-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-06-10 | — | — | WO | disclosed |