SCHEMBL7535

SCHEMBL7535

Cc1ccc2nc(N)sc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 1.00
MAPT P10636 3/20 1.00
SMN1; SMN2 Q16637 4/20 0.66
NPC1 O15118 3/20 0.66
GAA P10253 2/20 0.61
HTT P42858 2/20 0.61
AXL P30530 1/20 0.61
GFER P55789 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
CYP3A4 P08684 4/20 0.61
SCN4A P35499 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2C19 P33261 1/20 0.61
ALDH1A1 P00352 5/20 0.60
TSHR P16473 3/20 0.60
KDM4E B2RXH2 2/20 0.60
TP53 P04637 2/20 0.60
APP P05067 1/20 0.60
GLA P06280 1/20 0.60
PIK3CA P42336 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27790630 0.98 RAB9A (0.96) RAB9AMAPTSMN1; SMN2NPC1GAA
SCHEMBL4848589 0.87 MAPT (0.76) RAB9AMAPTSMN1; SMN2NPC1GAA
Fluorobenzene SCHEMBL27589692 0.87 RAB9A (0.76) RAB9AMAPTSMN1; SMN2NPC1GAA
SCHEMBL25303570 0.85 MAPT (0.74) RAB9AMAPTPIK3CAPI4KAPI4KB
SCHEMBL31114564 0.85 MAPT (0.74) RAB9AMAPTPIK3CAPI4KAPI4KB
SCHEMBL12262 0.84 MAPT (0.72) RAB9AMAPTSMN1; SMN2NPC1GAA
SCHEMBL29572251 0.84 MAPT (0.72) RAB9AMAPTSMN1; SMN2NPC1GAA
Methylpiperazine SCHEMBL29123764 0.82 RAB9A (0.68) RAB9AMAPTSMN1; SMN2NPC1GAA
SCHEMBL9722831 0.81 RAB9A (0.75) RAB9AMAPTSMN1; SMN2NPC1GAA
SCHEMBL13539413 0.81 RAB9A (0.68) RAB9AMAPTSMN1; SMN2NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775273-A Riluzole/ciprofloxacin heterozygote and derivative thereof, and preparation method and application thereof 赣南医科大学第一附属医院 2025-04-08 CN claimed
EP-3758697-B1 NOVEL ANTIMYCOBACTERIAL HETEROCYCLIC AMIDES CRESTONE INC (US) 2024-10-16 EP claimed
CN-118772080-A Antimycobacterial heterocyclic amides 克莱斯通公司 2024-10-15 CN claimed
CN-117209448-A Process for the preparation of (benzo) thiazole-containing thio/selenoacetamides and derivatives thereof 济宁医学院 2023-12-12 CN claimed
CN-117126119-A Preparation method of (benzo) thiazole amide-containing compound 济宁医学院 2023-11-28 CN claimed
CN-115466960-B Preparation method and application of benzothiazole group-containing modified polyaspartic acid fluorescent corrosion inhibitor 河北工业大学 2023-05-26 CN claimed
CN-115010591-B Paeonol eutectic crystal with thermal stability and solubility advantages and preparation method thereof 华东理工常熟研究院有限公司 2022-12-27 CN claimed
CN-115466960-A Preparation method and application of benzothiazole group-containing modified polyaspartic acid fluorescent corrosion inhibitor 河北工业大学 2022-12-13 CN claimed
CN-115010591-A Paeonol eutectic crystal with thermal stability and solubility advantages and preparation method thereof 华东理工常熟研究院有限公司 2022-09-06 CN claimed
CN-113045993-A Polishing solution for processing ultra-smooth low-damage bearing steel surface and application thereof 西南交通大学 2021-06-29 CN claimed
EP-0282971-B1 Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents WARNER LAMBERT CO (US) 1994-12-28 EP claimed
US-4826860-A STROKES WARNER-LAMBERT COMPANY (US) 1989-05-02 US claimed
EP-0282971-A2 Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents WARNER-LAMBERT COMPANY (US) 1988-09-21 EP claimed
US-4496727-A ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS CIBA-GEIGY CORPORATION (US) 1985-01-29 US claimed
US-4385174-A FOR PIGMENTS CIBA-GEIGY CORPORATION (US) 1983-05-24 US claimed
US-4363913-A Preparation of 2-aminobenzothiazoles EASTMAN KODAK COMPANY (US) 1982-12-14 US claimed
US-4349671-A Process for the production of metal complexes of isoindoline azines CIBA-GEIGY CORPORATION (US) 1982-09-14 US claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-4080493-A POLYBUTADIENE, POLYISOPRENE, GELATION INHIBITOR SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-21 US claimed
US-3933498-A Fogged, direct positive silver halide emulsions containing a bleach inhibiting compound and a Dmin maintainer compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-20 US claimed