SCHEMBL7535263

SCHEMBL7535263

[O]C1C=CC=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2526925 0.71
SCHEMBL9079161 0.67
SCHEMBL1639694 0.65
SCHEMBL10932125 0.65
SCHEMBL14685850 0.65
SCHEMBL929042 0.63
SCHEMBL28889610 0.63
SCHEMBL3850603 0.63 GPR84 (0.35)
SCHEMBL16313246 0.63
SCHEMBL14394010 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0020293-B1 STABILISING COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1984-05-23 EP claimed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US claimed
EP-2927229-B1 BENZENE-FUSED 5-MEMBERED NITROGEN-CONTAINING HETEROAROMATIC COMPOUNDS USEFUL FOR PROPHYLAXIS OR TREATMENT OF NEURODEGENERATIVE DISEASES OR EPILEPSY TAKEDA PHARMACEUTICALS CO (JP) 2018-09-05 EP disclosed
US-9296746-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-03-29 US disclosed
EP-2927229-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2015-10-07 EP disclosed
US-20150266872-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-09-24 US disclosed
EP-0823656-B1 Silver halide photographic light sensitive material KONISHIROKU PHOTO IND (JP) 2002-04-10 EP disclosed
EP-0196625-B1 RESOLUTION OF RACEMIC MIXTURES OF ALIPHATIC ACID ESTERS STAUFFER CHEMICAL COMPANY (US) 1992-10-28 EP disclosed
EP-0257716-A2 Improved process for conducting lipase enzyme hydrolysis STAUFFER CHEMICAL COMPANY (US) 1988-03-02 EP disclosed
US-4668628-A WATER SOLUBILITY, REDUCTION/PHYSICAL/, LIPASE, CANDIDA, HYDROLYSIS STAUFFER CHEMICAL COMPANY (US) 1987-05-26 US disclosed
EP-0196625-A2 Resolution of racemic mixtures of aliphatic acid esters STAUFFER CHEMICAL COMPANY (US) 1986-10-08 EP disclosed
US-4518773-A \"3-Carbamoyloxy cephalosporins\ BRISTOL-MYERS COMPANY (US) 1985-05-21 US disclosed
US-4426520-A CEPHALOSPORIN ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1984-01-17 US disclosed
US-4407755-A BACTERICIDAL PENICILLINS BRISTOL-MYERS COMPANY (US) 1983-10-04 US disclosed
US-4374982-A Cepham compounds BRISTOL-MYERS COMPANY (US) 1983-02-22 US disclosed
US-4322347-A 2-Carbamoyloxymethyl-penicillin derivatives BRISTOL-MYERS COMPANY (US) 1982-03-30 US disclosed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US disclosed