Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31598580 | 0.84 | MAPT (0.60) | TDP1TP53MAPTRAB9AMEN1 | |
| SCHEMBL19766263 | 0.83 | L3MBTL1 (0.61) | TDP1TP53MAPTRAB9AMEN1 | |
| SCHEMBL30022965 | 0.83 | RXFP1 (0.69) | TDP1TP53MAPTRAB9AMEN1 | |
| SCHEMBL505220 | 0.83 | RXFP1 (0.69) | TDP1TP53MAPTRAB9AMEN1 | |
| SCHEMBL20963100 | 0.83 | TP53 (0.60) | TP53MAPTRAB9AMEN1KMT2A | |
| SCHEMBL1098272 | 0.83 | TDP1 (0.79) | TDP1TP53RAB9AALDH1A1KDM4E | |
| SCHEMBL2295426 | 0.82 | MAPT (0.71) | TDP1TP53MAPTRAB9AMEN1 | |
| SCHEMBL9182432 | 0.82 | DHODH (0.55) | TP53MAPTRAB9AMEN1KMT2A | |
| SCHEMBL9182434 | 0.82 | DHODH (0.55) | TP53MAPTRAB9AMEN1KMT2A | |
| SCHEMBL21138402 | 0.81 | SMN1; SMN2 (0.65) | TP53MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002034251-A1 | TREATMENT OF ASTHMA WITH LFM ANALOGUES | PARKER HUGHES INSTITUTE (US) | 2002-05-02 | — | — | WO | disclosed |
| EP-1124795-A1 | INHIBITORS OF THE EGF-RECEPTOR TYROSINE KINASE AND THEIR USE | Parker Hughes Institute (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000056703-A1 | INHIBITORS OF THE EGF-RECEPTOR TYROSINE KINASE AND THEIR USE | PARKER HUGHES INSTITUTE (US) | 2000-09-28 | — | — | WO | disclosed |
| US-4046577-A | PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS | THE RICHARDSON COMPANY (US) | 1977-09-06 | — | — | US | disclosed |