Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.48 |
| ▸ | CTSL | P07711 | 13/20 | 0.48 |
| ▸ | CTSS | P25774 | 9/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563882 | 0.90 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7489396 | 0.89 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14131739 | 0.79 | CTSK (0.75) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5092491 | 0.78 | TP53 (0.49) | LMNATP53 | |
| SCHEMBL7449693 | 0.77 | CTSK (0.72) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4791555 | 0.76 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5092741 | 0.76 | CTSK (0.54) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5092743 | 0.76 | CTSK (0.54) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6407227 | 0.76 | CTSK (0.51) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5099281 | 0.75 | CTSK (0.56) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |