Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 10/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586131 | 0.84 | KCNH2 (0.51) | SLC6A4HTR1AHTR6 | |
| SCHEMBL6581206 | 0.83 | KCNH2 (0.53) | SLC6A4HTR1AHTR6HTR2A | |
| SCHEMBL6582403 | 0.77 | KCNH2 (0.50) | SLC6A4HTR1AHTR6 | |
| SCHEMBL6582493 | 0.76 | KCNH2 (0.52) | MPOSLC6A4HTR1AHTR6 | |
| SCHEMBL6581835 | 0.74 | KCNH2 (0.50) | MPOSLC6A4HTR1AHTR6 | |
| SCHEMBL6580870 | 0.71 | KCNH2 (0.67) | MPOSLC6A4HTR1AHTR6HTR2A | |
| SCHEMBL6582650 | 0.68 | KCNH2 (0.53) | SLC6A4HTR1AHTR6 | |
| SCHEMBL6593294 | 0.67 | HTR1A (0.71) | MPOSLC6A4HTR1AHTR6HTR2A | |
| SCHEMBL6589944 | 0.66 | HTR1A (0.61) | MPOSLC6A4HTR1AHTR6 | |
| SCHEMBL6582940 | 0.66 | KCNH2 (0.57) | SLC6A4HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246819-A1 | A METHOD FOR THE PREPARATION OF SUBSTITUTED BENZENE DERIVATIVES | H. Lundbeck A/S (DK) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049681-A1 | A METHOD FOR THE PREPARATION OF SUBSTITUTED BENZENE DERIVATIVES | H. LUNDBECK A/S (DK) | 2001-07-12 | — | — | WO | disclosed |