SCHEMBL7536048

SCHEMBL7536048

CCCCCCCC[Si](C)(C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.46
NR1H3 Q13133 1/20 0.46
CNR1 P21554 3/20 0.44
CNR2 P34972 3/20 0.44
KCNH2 Q12809 1/20 0.44
NAAA Q02083 1/20 0.41
MGAM O43451 1/20 0.39
DNM1 Q05193 1/20 0.39
EPHX1 P07099 3/20 0.39
EPHX2 P34913 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HTT P42858 1/20 0.39
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20482223 1.00 NR1H2 (0.46) NR1H2NR1H3CNR1CNR2KCNH2
SCHEMBL28960091 1.00 NR1H2 (0.46) NR1H2NR1H3CNR1CNR2KCNH2
SCHEMBL28899778 1.00 NR1H2 (0.46) NR1H2NR1H3CNR1CNR2KCNH2
SCHEMBL5801979 0.91 NR1H2 (0.53) NR1H2NR1H3CNR1CNR2NAAA
SCHEMBL18084487 0.89 MGAM (0.44) NR1H2NR1H3CNR1CNR2MGAM
SCHEMBL18717595 0.85 NR1H2 (0.59) NR1H2NR1H3CNR1CNR2KCNH2
SCHEMBL12879487 0.82 MAPT (0.42) NR1H2NR1H3MGAMALDH1A1TP53
SCHEMBL23014846 0.82 MGAM (0.37) NR1H2NR1H3CNR1CNR2MGAM
SCHEMBL23014927 0.82 NR1H2 (0.36) NR1H2NR1H3CNR1CNR2MGAM
SCHEMBL20483516 0.82 KCNH2 (0.42) KCNH2NAAADNM1EPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115397892-B Lipophilic silanes for anti-fingerprint coatings with high transparency, high abrasion resistance and low friction 巴斯夫欧洲公司 2024-05-24 CN claimed
CN-115397892-A Oleophilic silanes for fingerprint resistant coatings with high clarity, high abrasion resistance and low friction 巴斯夫欧洲公司 2022-11-25 CN claimed
EP-3195932-B1 HYDROSILYLATION REACTION CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-08-21 EP disclosed
CN-115397892-B Lipophilic silanes for anti-fingerprint coatings with high transparency, high abrasion resistance and low friction 巴斯夫欧洲公司 2024-05-24 CN disclosed
US-20230347328-A1 CATALYST, REDOX-SWITCHABLE CATALYST SYSTEM, AND RELATED METHODS INVOLVING HYDROSILYLATION DOW SILICONES CORPORATION 2023-11-02 US disclosed
US-20230347328-A1 CATALYST, REDOX-SWITCHABLE CATALYST SYSTEM, AND RELATED METHODS INVOLVING HYDROSILYLATION DOW SILICONES CORPORATION 2023-11-02 US disclosed
CN-115397892-A Oleophilic silanes for fingerprint resistant coatings with high clarity, high abrasion resistance and low friction 巴斯夫欧洲公司 2022-11-25 CN disclosed
CN-111033862-A Method for inhibiting decomposition of silyl ester compound 株式会社艾迪科 2020-04-17 CN disclosed
US-10005797-B2 Hydrosilylation reaction catalyst KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-06-26 US disclosed
US-20170233417-A1 HYDROSILYLATION REACTION CATALYST KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-08-17 US disclosed
EP-3195932-A1 HYDROSILYLATION REACTION CATALYST Kyushu University, National University Corporation (JP) 2017-07-26 EP disclosed
CN-1243778-C Polymerisation method CAMBRIDGE DISPLAY TECH LTD (GB) 2006-03-01 CN disclosed
CN-1364175-A Polymerisation method CAMBRIDGE DISPLAY TECH LTD (GB) 2002-08-14 CN disclosed
EP-1200504-A2 POLYMERISATION METHOD Cambridge Display Technology Limited (GB) 2002-05-02 EP disclosed
WO-2001007502-A2 POLYMERISATION METHOD CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2001-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233417-A1 HYDROSILYLATION REACTION CATALYST IDH1, IDH3A, IDH2 NR1H2 2979/4885NR1H3 2181/4885CNR1 4498/4885
US-10005797-B2 Hydrosilylation reaction catalyst IDH1, IDH3A, IDH2 NR1H2 2979/4885NR1H3 2181/4885CNR1 4498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.