Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482223 | 0.91 | NR1H2 (0.46) | NR1H2NR1H3CNR1CNR2MGAM | |
| SCHEMBL28899778 | 0.91 | NR1H2 (0.46) | NR1H2NR1H3CNR1CNR2MGAM | |
| SCHEMBL28960091 | 0.91 | NR1H2 (0.46) | NR1H2NR1H3CNR1CNR2MGAM | |
| SCHEMBL7536048 | 0.91 | NR1H2 (0.46) | NR1H2NR1H3CNR1CNR2MGAM | |
| SCHEMBL18084487 | 0.88 | MGAM (0.44) | NR1H2NR1H3CNR1CNR2MGAM | |
| SCHEMBL17124988 | 0.88 | NR1H2 (0.63) | NR1H2NR1H3CNR1CNR2ESR1 | |
| SCHEMBL12879487 | 0.86 | MAPT (0.42) | NR1H2NR1H3MGAMMAPTESR1 | |
| SCHEMBL18717595 | 0.84 | NR1H2 (0.59) | NR1H2NR1H3CNR1CNR2AR | |
| SCHEMBL17124989 | 0.84 | NR1H2 (0.59) | NR1H2NR1H3CNR1CNR2ESR1 | |
| Water SCHEMBL28197942 | 0.84 | MAPT (0.41) | NR1H2NR1H3MGAMMAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111033862-A | Method for inhibiting decomposition of silyl ester compound | 株式会社艾迪科 | 2020-04-17 | — | — | CN | disclosed |
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | US | disclosed |
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | US | disclosed |
| US-20160197275-A1 | EMITTER HAVING A CONDENSED RING SYSTEM | MERCK PATENT GMBH (DE) | 2016-07-07 | — | — | US | disclosed |
| US-9326513-B2 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-03 | — | — | US | disclosed |
| US-9326513-B2 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-03 | — | — | US | disclosed |
| US-20150340612-A1 | UV EMITTERS COMPRISING A MULTIPLE BOND | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150340612-A1 | UV EMITTERS COMPRISING A MULTIPLE BOND | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150303397-A1 | INORGANIC BARRIER LAYERS | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150270489-A1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20140335201-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | US | disclosed |
| US-8513286-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513286-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-20 | — | — | US | disclosed |
| CN-101307183-B | Epoxy-polysiloxane resin compositions, solid state devices encapsulated therewith and method | GEN ELECTRIC | 2011-06-29 | — | — | CN | disclosed |
| US-20110046088-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| CN-100480352-C | Epoxy resin composition, solid state device encapsulated therewith and method | GEN ELECTRIC (US) | 2009-04-22 | — | — | CN | disclosed |
| CN-101307183-A | Epoxy-polysiloxane resin compositions, solid state devices encapsulated therewith and method | GEN ELECTRIC (US) | 2008-11-19 | — | — | CN | disclosed |
| EP-1633750-A2 | SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAINDOLINES | Eisai Co., Ltd. (JP) | 2006-03-15 | — | — | EP | disclosed |
| CN-1534074-A | Solid state device encapsulated with epoxy resin composition and method | ͨ�õ�����˾ | 2004-10-06 | — | — | CN | disclosed |
| WO-2004078757-A2 | SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAIDONINES | EISAI CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046088-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | CD14, MYADM, MPO | NR1H2 2595/4885NR1H3 2951/4885CNR1 1305/4885 |
| US-20140335201-A1 | FUNGICIDAL COMPOSITIONS | CYP1B1, CYP4B1, DDT | NR1H2 2077/4885NR1H3 2146/4885CNR1 3690/4885 |
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | CYP1B1, CYP4B1, DDT | NR1H2 2077/4885NR1H3 2146/4885CNR1 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.