Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.53 |
| ▸ | FNTB | P49356 | 20/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477932 | 0.89 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| SCHEMBL7540064 | 0.88 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| SCHEMBL7536075 | 0.86 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL7533105 | 0.85 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL7533614 | 0.82 | FNTA (0.59) | FNTAFNTBPGGT1B | |
| SCHEMBL8432635 | 0.80 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| SCHEMBL8103827 | 0.80 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| SCHEMBL7474422 | 0.79 | CYP11B1 (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL7743601 | 0.78 | FNTA (0.61) | FNTAFNTBPGGT1B | |
| SCHEMBL7536083 | 0.77 | FNTA (0.48) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045844-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-1045844-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999028314-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-06-10 | — | — | WO | disclosed |