Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.46 |
| ▸ | CTSK | P43235 | 10/20 | 0.46 |
| ▸ | CTSL | P07711 | 8/20 | 0.44 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15792286 | 0.78 | CYP2D6 (0.39) | — | |
| SCHEMBL9967749 | 0.78 | — | — | |
| SCHEMBL6183239 | 0.77 | CTSL (0.66) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7456823 | 0.77 | CTSL (0.66) | CTSSCTSKCTSLCTSB | |
| SCHEMBL25327830 | 0.75 | KMT2A (0.50) | — | |
| SCHEMBL1934297 | 0.74 | — | — | |
| SCHEMBL19882812 | 0.74 | — | — | |
| SCHEMBL11336790 | 0.74 | — | — | |
| SCHEMBL19135317 | 0.74 | — | — | |
| SCHEMBL15791951 | 0.73 | CYP2D6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178958-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000055125-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |